In older patients, This can be critical to understand as polypharmacy is typical and can potentiate the risk of DDIs and ADRs. Therefore, concurrent consumption of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and This may improve or lessen efficacy/ADRs of your prescribed tramadol. https://hemalchem.com/product/o-dsmt/